Product Description

KIF15 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15310-50, ES15310-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human KIF15 AA range: 974-1024

Isotype: IgG

Target: KIF15

Specificity: This antibody detects endogenous levels of KIF15 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in testis, colon, thymus and in breast cancer,

Molecular Weight (Da): 153kD

Function: Function: Plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly
Similarity: Belongs to the kinesin-like protein family. KLP2 subfamily
Similarity: Contains 1 kinesin-motor domain
Subcellular Location: Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots. Detected during mitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis. Localizes at the central spindle at anaphase (By similarity). Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity). Colocalizes with actin in interphase (By similarity). Colocalizes in dendrites and in growth cone of axons with microtubules
Subunit: Interacts with MKI67 and TPX2
Tissue Specificity: Expressed in testis, colon, tymus and in breast cancer

Subcellular Location: Cytoplasm Cytoplasm, cytoskeleton, spindle Detected during the interphase in the cytoplasm as finely punctuate pattern and irregularly shaped dots Detected during mitosis on the mitotic spindle Colocalizes with TPX2 in mitosis Localizes at the central spindle at anaphase (By similarity) Localizes at the sites of invaginating cell membranes, a position that corresponds to the location of the contractile actomyosin ring of dividing cells (By similarity) Colocalizes with actin in interphase (By similarity) Colocalizes in dendrites and in growth cone of axons with microtubules (By similarity)

Storage and Stability: -20°C/1 year

Gene Name: KIF15 KLP2 KNSL7

Protein Name: KIF15

Mouse Gene ID: 209737

Mouse SwissProt Number: Q6P9L6

Rat Gene ID: 353302

Rat SwissProt Number: Q7TSP2

Research Use Only