Product Description

KIF4B Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9542-50, ES9542-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: kinesin family member 4B(KIF4B) Homo sapiens This gene is an intronless retrocopy of kinesin family member 4A. The protein encoded by this gene is a microtubule-based motor protein that plays vital roles in anaphase spindle dynamics and cytokinesis. [provided by RefSeq, Jul 2016],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: KIF4B

Specificity: KIF4B Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Specifically expressed in testis,

Observed Band (KD): 135kD

Function: Function: Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization
Sequence Caution: Contaminating sequence. Potential poly-A sequence
Similarity: Belongs to the kinesin-like protein family
Similarity: Belongs to the kinesin-like protein family. Chromokinesin subfamily
Similarity: Contains 1 kinesin-motor domain
Subcellular Location: Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stag

Subcellular Location: Nucleus matrix Cytoplasm, cytoskeleton

Storage and Stability: -20°C/1 year

Gene Name: KIF4B

Protein Name: Chromosome-associated kinesin KIF4B (Chromokinesin-B)

Research Use Only