Product Description

KINH Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15303-50, ES15303-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human KINH AA range: 64-114

Isotype: IgG

Target: KINH

Specificity: This antibody detects endogenous levels of KINH at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.266% sodium azide.

Expression: Muscle, Placenta, Uterus,

Observed Band (KD): 105kD

Fields: Endocytosis, Dopaminergic synapse, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Prion disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Non-small cell lung cancer

Function: Domain: Composed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization, and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles
Function: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes
Similarity: Belongs to the kinesin-like protein family
Similarity: Belongs to the kinesin-like protein family. Kinesin subfamily
Similarity: Contains 1 kinesin-motor domain
Subcellular Location: Uniformly distributed between soma and neurites in hippocampal neurons
Subunit: Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1 (By similarity). Interacts with

Subcellular Location: Cytoplasm, cytoskeleton Cytolytic granule membrane Lysosome membrane, Peripheral membrane protein, Cytoplasmic side Uniformly distributed between soma and neurites in hippocampal neurons

Storage and Stability: -20°C/1 year

Gene Name: KIF5B KNS KNS1

Protein Name: KINH

Mouse Gene ID: 16573

Mouse SwissProt Number: Q61768

Rat Gene ID: 117550

Rat SwissProt Number: Q2PQA9

Research Use Only