Product Description

Kininogen 1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26657-50, RA26657-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: kininogen 1 (KNG1) Homo sapiens This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Kininogen-1 (Alpha-2-thiol proteinase inhibitor) (Fitzgerald factor) (High molecular weight kininogen) (HMWK) (Williams-Fitzgerald-Flaujeac factor) [Cleaved into: Kininogen-1 heavy chain, T-kinin (Ile-Ser-Bradykinin), Bradykinin (Kallidin I), Lysyl-bradykinin (Kallidin II), Kininogen-1 light chain, Low molecular weight growth-promoting factor]

Clonality: Polyclonal

Dilution: IHC-p 1:50-200, WB 1:500-2000

Molecular Weight: 45-120

Protein Molecular Weight (kDa): 45-120

Storage: -20°C/1 year

Human Gene ID: 3827

Human SwissProt Number: P01042

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only