Product Description

Kir5.1 (phospho-S416) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67195-50, BS67195-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regμlated by the concentration of extracellμlar potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regμlation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolateral K+ recycling in distal tubμles, this process is critical for Na+ reabsorption at the tubμles (PubMed:24561201).

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, IHC, IF/IC

Alternate Names: KCNJ16, Inward rectifier potassium channel 16, Inward rectifier K(+) channel Kir5.1, Potassium channel inwardly rectifying subfamily J member 16

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Kir5.1 with a phosphorylation site at S416. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), IHC (1/50 - 1/200), IF/ICC (1/50 - 1/200)

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 156% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Kir5 protein.1 with a phosphorylation site at S416 protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NPI9

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only