Product Description

KLF2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15293-50, ES15293-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1, MIM 601974) and the selectin CD62L (SELL, MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Krueppel-like factor 2 (Lung krueppel-like factor)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human KLF2 AA range: 196-246

Isotype: IgG

Target: KLF2

Specificity: This antibody detects endogenous levels of KLF2 at Human/Mouse/Rat

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.70% sodium azide.

Expression: Brain, Hair follicle dermal papilla, Lung, Spleen,

Observed Band (KD): 38kD

Fields: FoxO signaling pathway, Apelin signaling pathway, Fluid shear stress and atherosclerosis

Function: Function: Binds to the CACCC box in the beta-globin gene promoter and activates transcription
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
Similarity: Contains 3 C2H2-type zinc fingers
Subunit: Interacts with WWP1

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: KLF2 LKLF

Protein Name: KLF2

Mouse Gene ID: 16598

Mouse SwissProt Number: Q60843

Rat Gene ID: 306330

Rat SwissProt Number: Q9ET58

Research Use Only