KLHL1 Monoclonal Antibody - BT-MCA4706

KLHL1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4706-50, BT-MCA4706-100

Citations, Manuals and MSDS Available upon request.

Background: The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved in this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.Tissue specificity: Highly expressed in brain.

Research Areas: Cell biology

Target Protein: KLHL1

Applications: ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3A8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: KLHL1

Immunogen: Purified recombinant fragment of human KLHL1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 82kDa

UniProt Accession: Q9NR64

Synonyms: MRP2, FLJ30047, KIAA1490, KLHL1

GeneID: 57626

Research Use Only