Product Description

KMT6 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16737-50, BZ16737-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: Q15910

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100

Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 98 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of KMT6 / EZH2 in HEK293 lysates using KMT6 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using KMT6 / EZH2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of KMT6 in Hela using KMT6 / EZH2 antibody.

Alternative Name: WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2

Immunogen: A synthesized peptide derived from human KMT6 / EZH2

Conjugate: Unconjugated

Modification: Unmodified