[KO Validated] DBI Rabbit PolymAb® - A28141PM

[KO Validated] DBI Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A28141PM-20, A28141PM-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Category: Monoclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 10-12 kDa

Observed Molecular Weight: 12 kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human/Mouse

GeneID: 1622/13167

SWISS: P07108/P31786

Alternate Names: EP; ACBP; ACBD1; CCK-RP; endozepine

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:2000 - 1:10000 IHC-P, 1:1000 - 1:4000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000) ，a sequential dilution method is strongly recommended to ensure measurement accuracy.

Research Areas: Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease.

NCBI Alias: DBI

Research Use Only