Product Description

KPNA1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6647-50, BS6647-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P52294

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Background: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KPNA1 polyclonal antibody detects endogenous levels of KPNA1 protein.

Bioworld Molecular Weight: ~ 60kDa, 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using KPNA1 antibody at 1:1000 dilution., Immunohistochemistry of paraffin-embedded human lung cancer using KPNA1 antibody at dilution of 1:100 (40x lens)., Immunohistochemistry of paraffin-embedded human esophagus using KPNA1 antibody at dilution of 1:100 (40x lens).
, Immunohistochemistry of paraffin-embedded human esophagus using KPNA1 antibody at dilution of 1:100 (40x lens).

Alternative Name: KPNA1; IPOA5; NPI-1; RCH2; SRP1

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human KPNA1 (NP_002255.3).

Conjugate: Unconjugated

Modification: Unmodified