KSP Cadherin Monoclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: MB66077-50, MB66077-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: The cadherins are a family of Ca2+-dependent adhesion molecμles that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellμlar domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-16, also known as Ksp-cadherin, is a type I membrane protein which is kidney-specific. Cadherin-16 is expressed exclusively in the basolateral membrane of renal tubμlar epithelial cells. The human Ksp-cadherin gene (cadherin-16) maps to chromosome 16q22.1. The mouse Ksp-cadherin gene was localized to a highly syntenic region of distal chromosome 8. Category: Primary Antibody Reactivity: Human Host: Mouse Applications: IHC Alternate Names: Cadherin-16, Kidney-specific cadherin, Ksp-cadherin Clonality: Monoclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human KSP Cadherin. The exact sequence is proprietary. Dilution: IHC (1/100 - 1/300) Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Specificity: Recognizes endogenous levels of KSP Cadherin protein. Molecular Weight: ~ 89 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: O75309 Product: Mouse IgG1. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide. Research Use Only