Product Description

Ksr2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26731-50, RA26731-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: domain:The protein kinase domain is predicted to be catalytically inactive., function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production., PTM:Phosphorylated on Ser-474 by MARK3., similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family., similarity:Contains 1 phorbol-ester/DAG-type zinc finger., similarity:Contains 1 protein kinase domain., subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF., tissue specificity:Mainly expressed in brain and kidney.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC-p, IF/ICC, ELISA

Alternate Names: KSR2, Kinase suppressor of Ras 2, hKSR2

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 108

Protein Molecular Weight (kDa): 108

Storage: -20°C/1 year

Human Gene ID: 283455

Human SwissProt Number: Q6VAB6

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only