Ku-80 (phospho Thr714) Polyclonal Antibody - RA26749

Ku-80 (phospho Thr714) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26749-50, RA26749-100

Citations, Manuals and MSDS Available upon request.

Background: X-ray repair cross complementing 5 (XRCC5) Homo sapiens The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V (D) J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V (D) J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 7520

Protein MW (KDa): 83

SWISS: P13010

Source: Rabbit

Research Use Only