Kv1.3 (phospho Tyr187) Polyclonal Antibody - RA26757

Kv1.3 (phospho Tyr187) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26757-50, RA26757-100

Citations, Manuals and MSDS Available upon request.

Background: potassium voltage-gated channel subfamily A member 3 (KCNA3) Homo sapiens Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: KCNA3; HGK5; Potassium voltage-gated channel subfamily A member 3; HGK5; HLK3; HPCN3; Voltage-gated K (+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3738

Protein MW (KDa): 58

SWISS: P22001

Source: Rabbit

Research Use Only