Product Description

Lactoferrin Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66784-50, MB66784-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Ferritin and transferrins manage necessary iron-binding fuctions for iron metabolism. Transferrins comprise a class of single-chain, two-sited, metal-binding proteins expressed throughout the fluid and cells of vertebrates. The three major types of transferrin include serotransferrin, lactotransferrin (lactoferrin) and ovotransferrin. Lactoferrin is found in milk, tears and leukocytes. It degrades an IgA1 protease secreted by Haemophilus influenzae and, consequently, allows the human IgA1 antibody to effectively abolish Haemophilus influenzae colonization. Lactoferrin also attenuates the pathogenic potential of Haemophilus influenzae by proteolytic degradation of the Hap adhesin. While lactoferrin may aid in the the transmission of human T cell leukemia virus type 1, it inhibits HIV-1 replication at the level of viral fusion and entry into cells. The inhibitory effects of lactoferrin on mixed lymphocyte reactions suggest that it may have the ability to sense the activation status of lymphocytes. The gene encoding human lactoferrin maps to chromosome 3q21.31.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB, IF/ICC

Alternate Names: GIG12, LF, Lactotransferrin, Lactoferrin, Growth-inhibiting protein 12, Talalactoferrin

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human Lactoferrin. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/4000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of Lactoferrin protein.

Molecular Weight: ~ 68 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02788

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only