LAL Monoclonal Antibody - BT-MCA3381

LAL Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3381-50, BT-MCA3381-100

Citations, Manuals and MSDS Available upon request.

Background: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

Research Areas: Others

Target Protein: LAL

Reactivity: Human

Clonality: Monoclonal

Clone ID: 9G7F12

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: LAL

Immunogen: Purified recombinant fragment of LAL expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P38571

Synonyms: LAL, CESD, LIPA

GeneID: 3988

Research Use Only