LC3 A/B Rabbit Polyclonal Antibody - BT-AP03381

LC3 A/B Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03381-20, BT-AP03381-50, BT-AP03381-100

Citations, Manuals and MSDS Available upon request.

Background: Probably involved in formation of autophagosomal vacuoles (autophagosomes).|PTM:The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form| LC3-I. This is activated by APG7L/ATG7| transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form| LC3-II.|Belongs to the MAP1 LC3 family.|subcellular location:LC3-II binds to the autophagic membranes.|subunit:3 different light chains| LC1| LC2 and LC3| can associate with MAP1A and MAP1B proteins.|tissue specificity:Most abundant in heart| brain| liver| skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.|

Research Areas: Cancer; Cardiovascular; Metabolism; Signal transduction; Neuroscience

Target Protein: LC3

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: LC3 A/B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 13310

UniProt Accession: Human: Q9H492/Q9GZQ8

Synonyms: LC3 A/B

Research Use Only