LPP Monoclonal Antibody - BT-MCA3507

LPP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3507-50, BT-MCA3507-100

Citations, Manuals and MSDS Available upon request.

Background: LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.

Research Areas: Signal transduction

Target Protein: LPP

Applications: WB, IHC, ICC

Reactivity: Human, Mouse, Monkey, Hamster

Clonality: Monoclonal

Clone ID: 8B3A11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: LPP

Immunogen: Purified recombinant fragment of human LPP expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 66kDa

UniProt Accession: Q93052

Synonyms: LPP

GeneID: 4026

Research Use Only