LRP5 Monoclonal Antibody - BT-MCA3804

LRP5 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3804-50, BT-MCA3804-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.

Research Areas: Cardiovascular, Metabolism, Neuroscience , Signal transduction, Stem cells

Target Protein: LRP5

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2B11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: LRP5

Immunogen: Purified recombinant fragment of human LRP5 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 179kDa

UniProt Accession: O75197

Synonyms: HBM, LR3, OPS, EVR1, EVR4, LRP7, OPPG, BMND1, OPTA1, VBCH2

GeneID: 4041

Research Use Only