LRRK2 Monoclonal Antibody - BT-MCA2374

LRRK2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2374-50, BT-MCA2374-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Research Areas: Neuroscience

Target Protein: LRRK2

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2A2A8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: LRRK2

Immunogen: Purified recombinant fragment of human LRRK2 (AA: 300-530) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 286kDa

UniProt Accession: Q5S007

Synonyms: PARK8, RIPK7, ROCO2, AURA17, DARDARIN

GeneID: 120892

Research Use Only