Product Description

LRRN2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15098-50, ES15098-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA, IHC

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human LRRN2 AA range: 296-346

Isotype: IgG

Target: LRRN2

Specificity: This antibody detects endogenous levels of LRRN2 at Human

Dilution: WB 1:500-2000, IHC-p 1:50-300, ELISA 2000-20000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Overamplified in malignant gliomas,

Molecular Weight (Da): 78kD

Function: Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain
Similarity: Contains 11 LRR (leucine-rich) repeats
Tissue Specificity: Overamplified in malignant gliomas

Subcellular Location: Membrane, Single-pass type I membrane protein

Storage and Stability: -20°C/1 year

Gene Name: LRRN2 GAC1 LRRN5 UNQ256/PRO293

Protein Name: LRRN2

Research Use Only