Product Description

Lrwd1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A21399-20, A21399-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 71kDa

Observed Molecular Weight: Refer to figures

Immunogen: Synthetic peptide .

Species: Human

GeneID: 222229

SWISS: Q9UFC0

Alternate Names: ORCA; CENP-33; Lrwd1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cell Biology & Developmental Biology.

NCBI Alias: LRWD1

Research Use Only