LysRS Monoclonal Antibody - BT-MCA0858

LysRS Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0858-50, BT-MCA0858-100

Citations, Manuals and MSDS Available upon request.

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and nuclear signaling

Target Protein: KARS

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Lysyl-tRNA synthetase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15046; Mouse: Q99MN1

Synonyms: KARS; KIAA0070; Lysine--tRNA ligase; Lysyl-tRNA synthetase; LysRS

GeneID: Human: 3735

Research Use Only