MAGEA1 (F293) Polyclonal Antibody-BS1217

MAGEA1 (F293) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1217-50, BS1217-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P43355/Q8WWH6

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of MAGE-1/Tumor antigen MAGE-N (F293) pAb in paraffin-embedded human breast carcinoma tissue.

Bioworld Molecular Weight: ~ 34, 46 kDa

Specificity: MAGE-1 (F293) polyclonal antibody detects endogenous levels of MAGE-1 protein. This antibody also detects endogenous levels of Tumor antigen MAGE-N.

Alternative Name: Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen; MAGEA1; MAGE1; MAGE1A; Tumor antigen MAGE-N

Immunogen: Synthetic peptide, corresponding to amino acids 280-320 of Human MAGE-1.

Conjugate: Unconjugated

Modification: Unmodified