Product Description

Mammaglobin B (K23) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1218-50, BS1218-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O75556

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC, IF

All Applications: IHC: 1:50~1:200
IF: 1:50~1:200

Background: Secretoglobins (also called lipophilins or mammaglobins) are small secreted proteins of ndocrine-responsive organs and mucosal epithelia that form multimeric complexes and correlate with the development of various human cancers. Lipophilin A and Lipophilin B are orthologs of prostatein estramustine- binding protein), the major secretory glycoprotein of the rat ventral prostate gland. Lipophilin A, also designated LIPA, LPHA and secretoglobin, family 1D, member 1 (SCGB1D1), is a component of a heterodimeric molecule present in human tears. Lipophilin B, also designated LIPB, LPHB and secretoglobin, family 1D, member 2 (SCGB1D2), mRNA can be overexpressed in breast tumors and shows a high degree of correlation with the mRNA expression profile of mammaglobin. Histological detection in breast tissue of Mammaglobin A, also designated MGB1 and secretoglobin, family 2A, member 2 (SCGB2A2) and Mammaglobin B, also designated MGB2, Lipophilin C, LPHC, UGB3 and SCGB2A2, is a reliable diagnostic marker for breast tumors

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Mammaglobin B (K23) pAb in paraffin-embedded human breast carcinoma tissue.

Bioworld Molecular Weight: ~ 11 kDa

Specificity: Mammaglobin B (K23) polyclonal antibody detects endogenous levels of Mammaglobin B protein

Alternative Name: Secretoglobin; Mammaglobin-B; Lacryglobin; Lipophilin-C; Mammaglobin-2; Secretoglobin family 2A member 1; SCGB2A1; LIPHC; MGB2; UGB3

Immunogen: Synthetic peptide, corresponding to amino acids 201-250 of Human Mammaglobin B.

Conjugate: Unconjugated

Modification: Unmodified