MAP4K4 Monoclonal Antibody - BT-MCA3123

MAP4K4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3123-50, BT-MCA3123-100

Citations, Manuals and MSDS Available upon request.

Background: MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research Areas: Signal Transduction

Target Protein: MAP4K4

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4H9E7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MAP4K4

Immunogen: Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: O95819

Synonyms: HGK, NIK

GeneID: 9448

Research Use Only