Product Description

Mash2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES6256-50, ES6256-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: achaete-scute family bHLH transcription factor 2(ASCL2) Homo sapiens This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: ASCL2, BHLHA45, HASH2, Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from Mash2. at AA range: 1-80

Isotype: IgG

Target: Mash2

Specificity: Mash2 Polyclonal Antibody detects endogenous levels of Mash2 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed specifically in the extravillous trophoblasts of the developing placenta,

Observed Band (KD): 25kD

Function: Function: AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system
Similarity: Contains 1 basic helix-loop-helix (bHLH) domain
Subunit: Efficient DNA binding requires dimerization with another bHLH protein
Tissue Specificity: Expressed specifically in the extravillous trophoblasts of the developing placenta

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ASCL2

Protein Name: Achaete-scute homolog 2

Mouse Gene ID: 17173

Mouse SwissProt Number: O35885

Rat Gene ID: 24209

Rat SwissProt Number: P19360

Research Use Only