MATK Monoclonal Antibody - BT-MCA4533

MATK Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4533-50, BT-MCA4533-100

Citations, Manuals and MSDS Available upon request.

Background: MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MATK

Applications: WB, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 9D7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MATK

Immunogen: Purified recombinant fragment of human MATK expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 56kDa

UniProt Accession: P42679

Synonyms: CHK, CTK

GeneID: 4145

Research Use Only