Matriptase Polyclonal Antibody - RA27056

Matriptase Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27056-50, RA27056-100

Citations, Manuals and MSDS Available upon request.

Background: suppression of tumorigenicity 14 (ST14) Homo sapiens The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: ST14; PRSS14; SNC19; TADG15; Suppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 6768

Protein MW (KDa): 95

SWISS: Q9Y5Y6

Source: Rabbit

Research Use Only