Product Description

MBD3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27066-50, RA27066-100

Citations, Manuals and MSDS Available upon request.

Background: methyl-CpG binding domain protein 3 (MBD3) Homo sapiens DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD) . The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 53615

Protein MW (KDa): 33

SWISS: O95983

Source: Rabbit

Research Use Only