MECOM Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-19826-60, E-AB-19826-120, E-AB-19826-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MECOM
Target Synonym: Ecotropic Virus Integration Site 1 Protein Homolog; MDS1 And EVI1 Complex Locus Protein; PR Domain 3; EVI1; MDS1; MDS1 And EVI1 Complex Locus Protein EVI1; MDS1 And EVI1 Complex Locus Protein MDS1; Ecotropic Viral Integration Site 1; Myelodysplasia Syndrome 1 Protein; Zinc Finger Protein Evi1; Oncogene EVI1; AML1-EVI-1; MDS1-EVI1; RUSAT2; KMT8E; PRDM3
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q03112
Background: The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Concentration: 1.68 mg/mL
Immunogen: Synthetic peptide of human MECOM
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only