MEK Kinase-2 Monoclonal Antibody - BT-MCA0874

MEK Kinase-2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0874-50, BT-MCA0874-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Research Areas: Signal transduction

Target Protein: MAP3K2

Applications: WB, IF, ICC, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Mitogen-activated protein kinase kinase kinase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y2U5; Mouse: Q61083

Synonyms: MAP3K2; MAPKKK2; MEKK2; Mitogen-activated protein kinase kinase kinase 2; MAPK; ERK kinase kinase 2; MEK kinase 2; MEKK 2

GeneID: Human: 10746

Research Use Only