MER Monoclonal Antibody - BT-MCA2823

MER Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2823-50, BT-MCA2823-100

Citations, Manuals and MSDS Available upon request.

Background: MER (c-mer proto-oncogene tyrosine kinase) is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. MER has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S have been identified as ligands for the UFO family of receptors. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Research Areas: Others

Target Protein: MER

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7E5G1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MER

Immunogen: Purified recombinant fragment of MER expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: Q12866

Synonyms: MER, RP38, c-mer, MGC133349, MERTK

GeneID: 10461

Research Use Only