Product Description

MER34 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES14974-50, ES14974-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Alternate Names: HERV-MER_4q12 provirus ancestral Env polyprotein (Endogenous retrovirus group MER34 member 1)

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human MER34 AA range: 391-441

Isotype: IgG

Target: MER34

Specificity: This antibody detects endogenous levels of MER34 at Human

Dilution: WB 1:500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.109% sodium azide.

Expression: Expressed at high level in the placenta and stem cells (at protein level) (PubMed:28739914), Also expressed in the kidney but at a lower level (PubMed:28739914), Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level) (PubMed:28739914),

Observed Band (KD): 60kD

Function: Function: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution
Similarity: Belongs to the gamma type-C retroviral envelope protein family

Subcellular Location: [Endogenous retroviral envelope protein HEMO]: Cell membrane, Single-pass type I membrane protein This uncleaved form present at the cell surface represents the major form (PubMed:28739914), [Endogenous retroviral envelope protein HEMO, secreted form]: Secreted This secreted form, which is released in the extracellular medium following cleavage, constitutes a minor form (PubMed:28739914)

Storage and Stability: -20°C/1 year

Gene Name: ERVMER34-1 LP9056

Protein Name: MER34

Research Use Only