Product Description

MLF1/MLF2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65449-50, BS65449-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Pig, Cow, Sheep

Host: Rabbit

Applications: IHC-P

Alternate Names: Hls7, MLF1, MLF2, MLF3, MLF1_HUMAN, Myelodysplasia myeloid leukemia factor 1, Myelodysplasia-myeloid leukemia factor 1, Myeloid leukemia factor 1, myeloid leukemia factor 1 variant 1, myeloid leukemia factor 1 variant 2, myeloid leukemia factor 1 variant 3.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human MLF1/2/3:165-268/268

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: MLF1/MLF2 Polyclonal Antibody detects endogenous levels of MLF1/MLF2 protein.

Molecular Weight: 31kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q71F23

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only