MLH1 Monoclonal Antibody - BT-MCA0886

MLH1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0886-50, BT-MCA0886-100

Citations, Manuals and MSDS Available upon request.

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Research Areas: Epigenetics and nuclear signaling; Cancer

Target Protein: MLH1

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: DNA mismatch repair protein Mlh1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P40692; Mouse: Q9JK91

Synonyms: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

GeneID: Human: 4292

Research Use Only