Product Description

MLH1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27270-50, RA27270-100

Citations, Manuals and MSDS Available upon request.

Background: mutL homolog 1 (MLH1) Homo sapiens This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

Applications: WB; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4292

Protein MW (KDa): 85

SWISS: P40692

Source: Rabbit

Research Use Only