MOX-2 (N184) Polyclonal Antibody-BS2006

MOX-2 (N184) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2006-50, BS2006-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P50222

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: MOX-1 and MOX-2 function transiently in the formation of mesodermal and mesenchymal derivatives. MOX-1 and MOX-2 are implicated in the early steps of mesoderm formation during gastrulation. In addition, the MOX proteins are also involved in somatic differentiation. Significantly, MOX-1 associates more strongly with Pax1, whereas MOX-2 preferentially associates with Pax3. Specifically, expression of MOX-2, also known as Mesenchyme homeobox 2 and GAX, has been shown to be critical in axial skeleton development. MOX-2 is not needed for the migration of myogenic precursors into the limb bud, but it is essential for normal appendicular muscle formation and for the normal regulation of myogenic genes. MOX-2 is expressed in placental tissue.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of MOX-2 (N184) pAb in paraffin-embedded human kidney carcinoma tissue at 1:50. showing cytoplasmic and nucleus staining. Negative control (the right) Using PBS instead of primary antibody,Secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~ 33 kDa

Specificity: MOX-2 (N184) polyclonal antibody detects endogenous levels of MOX-2 protein.

Alternative Name: Homeobox protein MOX-2; Growth arrest-specific homeobox; Mesenchyme homeobox 2; MEOX2; GAX; MOX2

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human MOX-2.

Conjugate: Unconjugated

Modification: Unmodified