Product Description

MRP-L46 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES2842-50, ES2842-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: MRPL46, C15orf4, LIECG2, 39S ribosomal protein L46, mitochondrial, L46mt, MRP-L46, P2ECSL

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPL46. AA range:111-160

Isotype: IgG

Target: MRP-L46

Specificity: MRP-L46 Polyclonal Antibody detects endogenous levels of MRP-L46 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Skeletal muscle, Spleen,

Observed Band (KD): 32kD

Function: Similarity: Belongs to the ribosomal protein L46 family

Subcellular Location: Mitochondrion

Storage and Stability: -20°C/1 year

Gene Name: MRPL46

Protein Name: 39S ribosomal protein L46 mitochondrial

Mouse Gene ID: 67308

Mouse SwissProt Number: Q9EQI8

Rat Gene ID: 293054

Rat SwissProt Number: Q5RK00

Research Use Only