MRPL22 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-19168-60, E-AB-19168-120, E-AB-19168-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MRPL22
Target Synonym: MRPL22; 39S ribosomal protein L22; 39S ribosomal protein L22 mitochondrial precursor; 39S ribosomal protein L25; 39S ribosomal protein L25; mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; mitochondrial; mitochondrial ribosomal protein L22; MRP L22; MRP L25; MRP-L22; MRP-L25; Mrpl22; RM22; RPML25
Research Areas: Epigenetics and Nuclear Signaling, Metabolism
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NWU5
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.9 mg/mL
Immunogen: Fusion protein of human MRPL22
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only