MSH2 Monoclonal Antibody - BT-MCA0897

MSH2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0897-50, BT-MCA0897-100

Citations, Manuals and MSDS Available upon request.

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Research Areas: Epigenetics and nuclear signaling; Cancer

Target Protein: MSH2

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: DNA mismatch repair protein Msh2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P43246; Mouse: P43247

Synonyms: MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

GeneID: Human: 4436

Research Use Only