MSI2 Monoclonal Antibody - BT-MCA3122

MSI2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3122-50, BT-MCA3122-100

Citations, Manuals and MSDS Available upon request.

Background: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous; detected at low levels.

Research Areas: Epigenetics and nuclear signaling

Target Protein: MSI2

Applications: WB, IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2C11

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MSI2

Immunogen: Purified recombinant fragment of human MSI2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 35kDa

UniProt Accession: Q96DH6

Synonyms: MSI2H, MGC3245, FLJ36569, MSI2

GeneID: 124540

Research Use Only