MTA1 Monoclonal Antibody - BT-MCA2874

MTA1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2874-50, BT-MCA2874-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MTA1

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7G9C10

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: MTA1

Immunogen: Purified recombinant fragment of human MTA1 (AA: 541-715) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 80.8kDa

UniProt Accession: Q13330

GeneID: 9112

Research Use Only