MTHFR Monoclonal Antibody - BT-MCA0904

MTHFR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0904-50, BT-MCA0904-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Research Areas: Signal transduction; Metabolism

Target Protein: MTHFR

Applications: WB, IHC-p, IF, ELISA

Reactivity: Human,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Methylenetetrahydrofolate reductase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P42898; Mouse: Q9WU20

Synonyms: MTHFR; Methylenetetrahydrofolate reductase

GeneID: Human: 4524

Research Use Only