Product Description

MVK Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27490-50, RA27490-100

Citations, Manuals and MSDS Available upon request.

Background: mevalonate kinase (MVK) Homo sapiens This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: MVK; Mevalonate kinase; MK

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Monkey

GeneID (Human): 4598

Protein MW (KDa): 42

SWISS: Q03426

Source: Rabbit

Research Use Only