MYC Monoclonal Antibody - BT-MCA2286

MYC Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2286-50, BT-MCA2286-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. (provided by RefSeq).

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: MYC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7E10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: MYC

Immunogen: Purified recombinant fragment of human MYC expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 49kDa

UniProt Accession: P01106

Synonyms: MRTL, c-Myc, bHLHe39

GeneID: 4609

Research Use Only