Product Description

MYH Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27504-50, RA27504-100

Citations, Manuals and MSDS Available upon request.

Background: mutY DNA glycosylase (MUTYH) Homo sapiens This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: MUTYH; MYH; A/G-specific adenine DNA glycosylase; MutY homolog; hMYH

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4595

Protein MW (KDa): 60

SWISS: Q9UIF7

Source: Rabbit

Research Use Only