Product Description

MYL9/MYL12A (P13) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1552-50, BS1552-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P24844/P19105

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC, IF

All Applications: IHC: 1:50~1:200
IF: 1:50~1:200

Background: Myosin regulatory light chains, including MRCL3 (also known as MRLC3 or MLCB), MRLC2 (also known as MLC-B) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analysis of MYL9/MYL12A (P13) pAb in paraffin-embedded human lung carcinoma tissue.

Bioworld Molecular Weight: ~ 20 kDa

Specificity: MYL9/MYL12A (P13) polyclonal antibody detects endogenous levels of MYL9 and MYL12A protein.

Alternative Name: Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; Short name=LC20; MLC-2C; Myosin RLC; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; MLC2; MRLC1; MYRL2; Myosin regulatory light chain 12A; MLC-2B; Myosin RLC; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain MRLC3; MYL12A; MLCB; MRLC3; RLC

Immunogen: Synthetic peptide, corresponding to the 10-40 of Human MYL9.

Conjugate: Unconjugated

Modification: Unmodified