Product Description

Myosin VI Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27539-50, RA27539-100

Citations, Manuals and MSDS Available upon request.

Background: myosin VI (MYO6) Homo sapiens This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: MYO6; KIAA0389; Unconventional myosin-VI; Unconventional myosin-6

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4646

Protein MW (KDa): 149

SWISS: Q9UM54

Source: Rabbit

Research Use Only