NAIP Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16924-20, A16924-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Rat
Protein Weight: 160kDa
Observed Molecular Weight: 160kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 4671
SWISS: Q13075
Alternate Names: BIRC1; NLRB1; psiNAIP; NAIP
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Apoptosis.
NCBI Alias: NAIP
Research Use Only